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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS003171619
Molecular formula	C21H16ClN3O3
IUPAC name	N-[3-chloro-4-[(1S,2R,6S,7R)-3,5-dioxo-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl]phenyl]pyridine-2-carboxamide
Molecular weight	393.827
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.6
Synonyms	SMR001875504 CHEBI:92530 NCGC00386910-01
Inchi Key	LJUABYFUJVRUSJ-FRVJLOGJSA-N
Inchi ID	InChI=1S/C21H16ClN3O3/c22-14-10-13(24-19(26)15-3-1-2-8-23-15)6-7-16(14)25-20(27)17-11-4-5-12(9-11)18(17)21(25)28/h1-8,10-12,17-18H,9H2,(H,24,26)/t11-,12+,17-,18+
PubChem CID	54752951
ChEMBL	CHEMBL1921961
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
189224	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
189226	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
189222	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
189221	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
189223	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
189225	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915

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