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Ligand

NameGalanin (1-29), porcine
Molecular formulaC144H210N42O39
IUPAC name3-[[2-[[2-[[2-[[2-[[2-[[4-amino-2-[[2-[[2-[2-[[2-[[1-[2-[[2-[[2-[[2-[[2-[2-[[2-[[4-amino-2-[[2-[[2-[[2-[(2-aminoacetyl)amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]propanoylamino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoylamino]-3-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-[[6-amino-1-[[1-[[2-[(1-amino-4-methyl-1-oxopentan-2-yl)amino]-2-oxoethyl]amino]-4-(4-hydroxyphenyl)-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-oxobutanoic acid
Molecular weight3153.52
Hydrogen bond acceptor45
Hydrogen bond donor44
XlogP-11.0
SynonymsGalanin [D-Trp2], porcine
BDBM85169
Inchi KeyNUGXOOKVHNJHDS-UHFFFAOYSA-N
Inchi IDInChI=1S/C144H210N42O39/c1-14-75(10)118(142(224)181-106(57-117(200)201)137(219)177-103(54-110(147)192)134(216)175-101(52-84-61-153-69-161-84)132(214)169-91(29-22-42-155-144(150)151)126(208)182-108(67-188)140(222)173-98(48-80-24-16-15-17-25-80)131(213)174-102(53-85-62-154-70-162-85)133(215)178-105(56-116(198)199)136(218)168-90(28-20-21-41-145)125(207)170-92(40-35-79-31-36-86(190)37-32-79)123(205)158-64-113(195)165-93(120(149)202)44-71(2)3)184-122(204)77(12)164-127(209)100(51-83-60-152-68-160-83)179-141(223)109-30-23-43-186(109)115(197)65-159-124(206)94(45-72(4)5)171-128(210)95(46-73(6)7)172-130(212)97(49-81-33-38-87(191)39-34-81)167-114(196)63-157-121(203)76(11)163-139(221)107(66-187)183-135(217)104(55-111(148)193)176-129(211)96(47-74(8)9)180-143(225)119(78(13)189)185-138(220)99(166-112(194)58-146)50-82-59-156-89-27-19-18-26-88(82)89/h15-19,24-27,31-34,36-39,59-62,68-78,90-109,118-119,156,187-191H,14,20-23,28-30,35,40-58,63-67,145-146H2,1-13H3,(H2,147,192)(H2,148,193)(H2,149,202)(H,152,160)(H,153,161)(H,154,162)(H,157,203)(H,158,205)(H,159,206)(H,163,221)(H,164,209)(H,165,195)(H,166,194)(H,167,196)(H,168,218)(H,169,214)(H,170,207)(H,171,210)(H,172,212)(H,173,222)(H,174,213)(H,175,216)(H,176,211)(H,177,219)(H,178,215)(H,179,223)(H,180,225)(H,181,224)(H,182,208)(H,183,217)(H,184,204)(H,185,220)(H,198,199)(H,200,201)(H4,150,151,155)
PubChem CID91898926
ChEMBLN/A
IUPHARN/A
BindingDB85169
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand has more than 10 hydrogen bond acceptor.
This ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
232311Galanin receptor type 1Q62805Galr1Rattus norvegicus (Rat)346
232312Galanin receptor type 1P47211GALR1Homo sapiens (Human)349
232309Galanin receptor type 2O08726Galr2Rattus norvegicus (Rat)372
232310Galanin receptor type 2O43603GALR2Homo sapiens (Human)387
232308Galanin receptor type 3O88626Galr3Rattus norvegicus (Rat)370
232313Galanin receptor type 3O60755GALR3Homo sapiens (Human)368

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