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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2036311
Molecular formula	C28H32N2O4S
IUPAC name	4-[2-[(2R)-2-[(E,3S)-3-hydroxy-4-[3-(1H-indol-5-yl)phenyl]but-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]butanoic acid
Molecular weight	492.634
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.7
Synonyms	BDBM50385121 SCHEMBL10210685
Inchi Key	NUXMYQHRAUGVMF-RSURJUNSSA-N
Inchi ID	InChI=1S/C28H32N2O4S/c31-25(9-7-24-8-11-27(32)30(24)14-16-35-15-2-5-28(33)34)18-20-3-1-4-21(17-20)22-6-10-26-23(19-22)12-13-29-26/h1,3-4,6-7,9-10,12-13,17,19,24-25,29,31H,2,5,8,11,14-16,18H2,(H,33,34)/b9-7+/t24-,25+/m0/s1
PubChem CID	57893867
ChEMBL	CHEMBL2036311
IUPHAR	N/A
BindingDB	50385121
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
232759	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
232760	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
232762	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
232761	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488
232763	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513

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