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Ligand

Nameleukotriene E4
Molecular formulaC23H37NO5S
IUPAC name(5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-amino-2-carboxyethyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid
Molecular weight439.611
Hydrogen bond acceptor7
Hydrogen bond donor4
XlogP2.1
Synonyms1826AH
BSPBio_001370
GTPL3352
NCGC00163400-01
[5S-[5R*,6S*(S*),7E,9E,11Z,14Z]]- 6-[(2-amino-2-carboxyethyl)thio]-5-hydroxy-7,9,11,14-Eicosatetraenoate
[ Show all ]
Inchi KeyOTZRAYGBFWZKMX-FRFVZSDQSA-N
Inchi IDInChI=1S/C23H37NO5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21(30-18-19(24)23(28)29)20(25)15-14-17-22(26)27/h6-7,9-13,16,19-21,25H,2-5,8,14-15,17-18,24H2,1H3,(H,26,27)(H,28,29)/b7-6-,10-9-,12-11+,16-13+/t19-,20-,21+/m0/s1
PubChem CID5280879
ChEMBLCHEMBL509456
IUPHAR5863, 3352
BindingDB50297387
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5545142-oxoglutarate receptor 1Q6IYF8Oxgr1Mus musculus (Mouse)337
554511Cysteinyl leukotriene receptor 1Q9Y271CYSLTR1Homo sapiens (Human)337
554512Cysteinyl leukotriene receptor 2Q9NS75CYSLTR2Homo sapiens (Human)346
556437Leukotriene B4 receptor 1Q15722LTB4RHomo sapiens (Human)352
461378Leukotriene B4 receptor 2Q9NPC1LTB4R2Homo sapiens (Human)358
250374P2Y purinoceptor 12Q9H244P2RY12Homo sapiens (Human)342
554513Uracil nucleotide/cysteinyl leukotriene receptorQ6NS65Gpr17Mus musculus (Mouse)339

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