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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL260674
Molecular formula	C20H14ClFN2O5
IUPAC name	2-[(3R)-5-chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxospiro[indole-3,3'-pyrrolidine]-1-yl]acetic acid
Molecular weight	416.789
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.8
Synonyms	Spiro-indolinone analogue, (R)-58 ZINC14976624 BDBM21603 SCHEMBL2482377 2-[(3R)-5-chloro-1''-[(2-fluorophenyl)methyl]-1,2-dihydrospiro[indole-3,3''-pyrrolidine]-2,2'',5''-trione]acetic acid
Inchi Key	SKLDVYDFQCXARY-HXUWFJFHSA-N
Inchi ID	InChI=1S/C20H14ClFN2O5/c21-12-5-6-15-13(7-12)20(18(28)23(15)10-17(26)27)8-16(25)24(19(20)29)9-11-3-1-2-4-14(11)22/h1-7H,8-10H2,(H,26,27)/t20-/m1/s1
PubChem CID	24776302
ChEMBL	CHEMBL260674
IUPHAR	N/A
BindingDB	21603
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
316571	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
316569	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
316570	Prostaglandin D2 receptor 2	Q9Z2J6	Ptgdr2	Mus musculus (Mouse)	382
316568	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358

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