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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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Ligand

Namebrimonidine
Molecular formulaC11H10BrN5
IUPAC name5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
Molecular weight292.14
Hydrogen bond acceptor3
Hydrogen bond donor2
XlogP0.6
SynonymsCHEMBL844
Tox21_110299
D0AE3X
UK 14308
E6GNX3HHTE
[ Show all ]
Inchi KeyXYLJNLCSTIOKRM-UHFFFAOYSA-N
Inchi IDInChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)
PubChem CID2435
ChEMBLCHEMBL844
IUPHAR520
BindingDB34572
DrugBankDB00484

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 13
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
4039645-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
403975Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
457747Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
546861Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
403972Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
403971Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
403966Alpha-2A adrenergic receptorP18871ADRA2ASus scrofa (Pig)450
403968Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
403974Alpha-2A adrenergic receptorQ01338Adra2aMus musculus (Mouse)450
403967Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
403970Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
403973Alpha-2B adrenergic receptorO77715ADRA2BDidelphis virginiana (North American opossum)382
403965Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462

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