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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL352131
Molecular formula	C22H20N4O2
IUPAC name	N-[(1R,2R)-2-aminocyclohexyl]-7-oxobenzo[e]perimidine-4-carboxamide
Molecular weight	372.428
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.4
Synonyms	7-Oxo-7H-benzo[e]perimidine-4-carboxylic acid ((1R,2R)-2-amino-cyclohexyl)-amide BDBM50075920 N-[(1R)-2alpha-Aminocyclohexane-1beta-yl]-7-oxo-7H-benzo[e]perimidine-4-carboxamide
Inchi Key	YEIPENKZKGYLPU-IAGOWNOFSA-N
Inchi ID	InChI=1S/C22H20N4O2/c23-16-7-3-4-8-17(16)26-22(28)15-10-9-14-18-19(24-11-25-20(15)18)12-5-1-2-6-13(12)21(14)27/h1-2,5-6,9-11,16-17H,3-4,7-8,23H2,(H,26,28)/t16-,17-/m1/s1
PubChem CID	15381045
ChEMBL	CHEMBL352131
IUPHAR	N/A
BindingDB	50075920
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
408119	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
408120	Corticotropin-releasing factor receptor 2	Q60748	Crhr2	Mus musculus (Mouse)	411

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