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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

Name5-hydroxytryptamine receptor 5B
SpeciesMus musculus (Mouse)
GeneHtr5b
SynonymMR22
HTR5B
GPR134
G protein-coupled receptor 134
5-HT-5B
[ Show all ]
DiseaseN/A for non-human GPCRs
Length370
Amino acid sequenceMEVSNLSGATPGLAFPPGPESCSDSPSSGRSMGSTPGGLILPGREPPFSAFTVLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAVLVMPLSLVSELSAGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRSRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYLPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPPESEMVFTARRRATVTFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELISPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR
UniProtP31387
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHAR648
DrugBankN/A

Known ligands

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Total entries: 16
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
117432D structurepropranololC16H21NO2259.3493 / 23.0Yes
136562D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
266242D structureYohimbineC21H26N2O3354.454 / 22.9Yes
838662D structureKetanserinC22H22FN3O3395.4345 / 12.6Yes
1711752D structure15532-75-9C11H13F3N2230.2345 / 12.3Yes
1748872D structuremethysergideC21H27N3O2353.4663 / 22.3Yes
1756442D structuresumatriptanC14H21N3O2S295.4014 / 20.9Yes
1766922D structureRU 24969C14H16N2O228.2952 / 21.8Yes
5544582D structure[125I]lysergideC20H24IN3O447.3372 / 13.6Yes
2903202D structureserotoninC10H12N2O176.2192 / 30.2Yes
2990392D structuremethiothepinC20H24N2S2356.5464 / 04.2Yes
3130012D structuredl-ArterenolC8H11NO3169.184 / 4-1.2Yes
3641102D structureBufotenineC12H16N2O204.2732 / 21.2Yes
3671752D structuredopamineC8H11NO2153.1813 / 3-1.0Yes
3759702D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
3882532D structureERGOTAMINEC33H35N5O5581.6736 / 32.0No

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