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Ligand

NameSCHEMBL1717163
Molecular formulaC21H22FN3O2
IUPAC name[(2R,5R)-5-[(5-fluoropyridin-2-yl)oxymethyl]-2-methylpiperidin-1-yl]-(1H-indol-7-yl)methanone
Molecular weight367.424
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP3.7
SynonymsUS8569311, 1-27
CHEMBL3655678
BDBM104705
Inchi KeyAZVRNCHGYXJASK-HUUCEWRRSA-N
Inchi IDInChI=1S/C21H22FN3O2/c1-14-5-6-15(13-27-19-8-7-17(22)11-24-19)12-25(14)21(26)18-4-2-3-16-9-10-23-20(16)18/h2-4,7-11,14-15,23H,5-6,12-13H2,1H3/t14-,15-/m1/s1
PubChem CID25127170
ChEMBLCHEMBL3655678
IUPHARN/A
BindingDB104705
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
18521Orexin receptor type 1P56718Hcrtr1Rattus norvegicus (Rat)416
18520Orexin receptor type 2P56719Hcrtr2Rattus norvegicus (Rat)460

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