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Ligand

Namepilocarpine
Molecular formulaC11H16N2O2
IUPAC name(3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one
Molecular weight208.261
Hydrogen bond acceptor3
Hydrogen bond donor0
XlogP1.1
SynonymsQCHFTSOMWOSFHM-WPRPVWTQSA-N
Imidazole-5-butyric acid, alpha-ethyl-beta-(hydroxymethyl)-1-methyl-, gamma-lactone
SPBio_001287
KBio2_004155
(+)-Pilocarpine
[ Show all ]
Inchi KeyQCHFTSOMWOSFHM-WPRPVWTQSA-N
Inchi IDInChI=1S/C11H16N2O2/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h5,7-8,10H,3-4,6H2,1-2H3/t8-,10-/m0/s1
PubChem CID5910
ChEMBLCHEMBL550
IUPHAR305
BindingDB50008072
DrugBankDB01085

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
274812Muscarinic acetylcholine receptor DM1P16395mAChR-ADrosophila melanogaster (Fruit fly)805
274813Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
274815Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
274816Muscarinic acetylcholine receptor M1P12657Chrm1Mus musculus (Mouse)460
274814Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466
274817Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466
274819Muscarinic acetylcholine receptor M3P20309CHRM3Homo sapiens (Human)590
274820Muscarinic acetylcholine receptor M4P08173CHRM4Homo sapiens (Human)479
274818Muscarinic acetylcholine receptor M5P08912CHRM5Homo sapiens (Human)532

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