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Ligand

NameOpc-4392
Molecular formulaC24H29N3O2
IUPAC name7-[3-[4-(2,3-dimethylphenyl)piperazin-1-yl]propoxy]-1H-quinolin-2-one
Molecular weight391.515
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.0
Synonyms7-(3-(4-(2,3-Dimethylphenyl)piperazinyl)propoxy)-2(1H)-quinolone
CAS_163839
111073-34-8
D09ULA
SCHEMBL2424904
[ Show all ]
Inchi KeyRRLWEQBPSAFVAS-UHFFFAOYSA-N
Inchi IDInChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28)
PubChem CID163839
ChEMBLN/A
IUPHAR268
BindingDB82065
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
3033295-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
5547675-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
303328D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
303327D(1B) dopamine receptorP25115Drd5Rattus norvegicus (Rat)475
556681D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
556682D(3) dopamine receptorP19020Drd3Rattus norvegicus (Rat)446
303331D(4) dopamine receptorP30729Drd4Rattus norvegicus (Rat)387

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