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Ligand

NameSB 204741
Molecular formulaC14H14N4OS
IUPAC name1-(1-methylindol-5-yl)-3-(3-methyl-1,2-thiazol-5-yl)urea
Molecular weight286.353
Hydrogen bond acceptor3
Hydrogen bond donor2
XlogP2.4
Synonyms3-(3-METHYL-1,2-THIAZOL-5-YL)-1-(1-METHYLINDOL-5-YL)UREA
BDBM84991
CTK8F0087
HMS3369K08
MLS000862184
[ Show all ]
Inchi KeyUSFUFHFQWXDVMH-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19)
PubChem CID3277600
ChEMBLCHEMBL323356
IUPHAR221
BindingDB84991
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 23
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
3442915-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
3442895-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
3442805-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
3442815-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
3442865-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
3442785-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5568905-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
3442775-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
3442905-hydroxytryptamine receptor 2BP30994Htr2bRattus norvegicus (Rat)479
3442765-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
3442925-hydroxytryptamine receptor 2CP34968Htr2cMus musculus (Mouse)459
3442935-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
3442955-hydroxytryptamine receptor 4Q29006HTR4Sus scrofa (Pig)137
344282Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
344287Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
344284D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
344283D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
344296D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
344279Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488
344288Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460

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