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Ligand

NameSB-649868
Molecular formulaC26H24FN3O3S
IUPAC nameN-[[(2S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Molecular weight477.554
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP5.2
Synonyms380899-24-1
CS-7584
N-((1-((5-(4-Fluorophenyl)-2-methyl-4-thiazolyl)carbonyl)-2-piperidinyl)methyl)-4-benzofurancarboxamide
SCHEMBL8045969
EX-A2570
[ Show all ]
Inchi KeyZJXIUGNEAIHSBI-IBGZPJMESA-N
Inchi IDInChI=1S/C26H24FN3O3S/c1-16-29-23(24(34-16)17-8-10-18(27)11-9-17)26(32)30-13-3-2-5-19(30)15-28-25(31)21-6-4-7-22-20(21)12-14-33-22/h4,6-12,14,19H,2-3,5,13,15H2,1H3,(H,28,31)/t19-/m0/s1
PubChem CID25195495
ChEMBLCHEMBL1272307
IUPHAR4461
BindingDB50417257
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
430287Orexin receptor type 1O43613HCRTR1Homo sapiens (Human)425
430288Orexin receptor type 1P56718Hcrtr1Rattus norvegicus (Rat)416
430286Orexin receptor type 2O43614HCRTR2Homo sapiens (Human)444
430289Orexin receptor type 2P56719Hcrtr2Rattus norvegicus (Rat)460

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